Principal Scientist

Pfizer Inc.

Cambridge, MA

Job posting number: #7262284 (Ref:pf-4915841)

Posted: July 11, 2024

Job Description

Why Patients Need You

Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

What You Will Achieve

The Hematology group in the Internal Medicine Research Unit (IMRU) is seeking a highly talented and motivated scientist to drive exploration of new pathways to identify and develop new therapies for chronic anemias and related blood disorders. The candidate will be involved in drug discovery research projects from early target identification to drug development and will thrive in a multidisciplinary team environment requiring excellent oral and written communication skills.

The successful candidate must demonstrate:

  • Advanced knowledge of the principles, concepts, and practices in red blood cell biology and hematopoiesis.
  • Ability to work collaboratively with subject matter experts to integrate data from multiple sources.
  • Innovation and self-motivation, capable of working independently as well as in the team setting.

How You Will Achieve It

  • Act as Biology lead for Hematology programs, developing and executing Biology strategy. Participate in team meetings by presenting experimental plans and results
  • Develop proposals for potential new targets to treat key unmet medical needs based on a combination of literature and internal/external data sets
  • Design and execute experiments and create innovative processes to characterize impacts to red blood cell health in relevant in vitro and in vivo models
  • Collaborate with scientists across the Research Unit to advance new targets for portfolio programs
  • Participate in team meetings by presenting experimental plans and results
  • Contribute to collaborations with leading academic labs to enable internal research programs
  • Supervise 2+ lab-based colleagues
  • Work closely with the Hematology lab head and lab operations to set up the lab and identify key equipment and instruments necessary for hematology research programs
  • Strive to publish scientific and methodological results in high quality journals
  • Collaborate with key internal and external hematology scientists to drive improved understanding of disease pathophysiology at the level of molecular pathways

Qualifications

  • Ph.D. in biology or related scientific field with 5+ years of relevant hematology experience or Bachelor’s with 12+ years of relevant hematology experience in a biopharma/biotech setting, using innovative in vitro and in vivo disease model systems to solve biological problems
  • Advanced knowledge of hematopoiesis and red blood cell biology
  • Recognized as a technical expert of research methods and preclinical models used to study disorders of hematopoiesis and erythropoiesis
  • Extensive experience with primary cell culture and flow cytometry
  • Experience as a Biology lead on Hematology projects
  • Demonstrated ability to train, manage and support 1-2 lab scientists
  • Excellent verbal and written communication skills
  • Proficiency in the use of Word processing, Excel, PowerPoint and relevant scientific software


Work Location Assignment:On Premise


The annual base salary for this position ranges from $99,900.00 to $166,500.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 15.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

Research and Development



Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.


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More Info

Job posting number:#7262284 (Ref:pf-4915841)
Application Deadline:Open Until Filled
Employer Location:Pfizer Inc.
New York,New York
United States
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