Job Description

Job Overview
The University of Cincinnati’s James L. Winkle College of Pharmacy (COP) and the College of Medicine’s (COM’s) Department of Internal Medicine announce a tenure-track faculty position of associate professor rank for an accomplished mid-career medicinal chemist. The successful applicant for the Winkle Chair in Medicinal Chemistry will serve as the medicinal chemistry director for the emerging Cancer Drug Development Institute (CDDI) at the University of Cincinnati (UC). The CDDI will be under the UC Cancer Center, comprised of investigators in the COM, COP, Cincinnati Children’s Hospital Medical Center, and UC Health (clinical arm of adult cancer medicine). The position’s planned start date is August 15, 2024 so that the medicinal chemistry lab will be operational before the end of the calendar year, independent of the CDDI timetable. Primary and secondary faculty appointments will be in the COP and COM, respectively. A ~2000 sq. ft. medicinal chemistry laboratory space plus additional labs for computational and drug assay work are immediately available to the hire, along with a generous start-up package.

Essential Functions
Serve as Director for CDDI at the University of Cincinnati;
Collaborate as co-investigator with UC cancer researchers toward achieving NCI program project grants and novel lead compound design, discovery and development
Obtain PI-level external funding and development of an independent research program are encouraged to the extent that time remains for collaboration with UC cancer researchers
Minimal teaching of medicinal chemistry classes may be expected, depending on research workload.
Attend meetings, participate in governance, prepare materials for teaching.
Serve on college or university committees and participate in curriculum development activities.
Review, and where necessary, respond in a timely manner to all University-related communications.
Other related duties as assigned.
Minimum Requirements
PHD in medicinal chemistry or synthetic organic chemistry, prior to effective date of appointment.
Demonstrated excellence in teaching and research evidenced by strong publication record in peer-reviewed journals. Candidates for a tenured appointment should demonstrate intellectual leadership and impact on the field and potential significant contributions to the department, University of Cincinnati, and wider scholarly community.
Experience with design/synthesis of PROTACs and other targeted protein degradation systems, commercialization of new molecular entities, and authorships on patents is desirable but not required.
Evidence of extramural funding history; Provision of partial salary support via external funding.
Experience in computational chemistry, virtual drug design and hit-to-lead compound discovery.