ROLE SUMMARY

The Platform: The Chief Medical Affairs Office’s Real World Evidence (RWE) Platform is responsible for establishing global scientific leadership and stature through the generation of integrated, end-to-end observational real-world evidence serving all therapeutic areas from proof of concept (POC) trials through LOE for priority pipeline candidates, pipeline supplementation through business development, and marketed inline products. The Platform fully centralizes RWE, epidemiology, outcomes research, RW-relevant health informatics, and biostatistics talent from global, US, international markets into one team to drive efficiency through internalized work.

The Platform functions to:

Enhance Pfizer’s ability to determine unmet medical needs; support differentiated product labels for Product Development programs including finding alternatives and accelerated licensure pathways for new indications through the use of Real World Data (RWD), Real World Insights (RWI) and Real World Evidence (RWE); inform clinical practice on appropriate prescription and use of Pfizer’s products; in collaboration with Access & Value, strengthen the value evidence package for payers and access/policy decision-makers; support measurement of short- and long-term impact of Pfizer’s products to both patients and populations; support competitive differentiation.

The Opportunity: This role will be responsible for intaking franchise and asset integrated evidence plans and tactics, then delivering high quality RWE, RW insights or other patient-centric evidence for prioritized projects to fully the tactic or strategic pillar, as directed by their supervisor in accordance with the RWE Strategic Planning Oncology team based on cross-functional partners’ strategic priorities.

The remit spans from global and prioritized international markets, where the evidence will be used to respond to regulatory commitments / requests, HTA/government entity needs and key projects that have been prioritized in a managed work queue by the global medical strategy committee. The role is highly technical and will execute hands-on evidence generation via a combinatorial approach of cutting edge retrospective data analyses, site-based evaluations (e.g., Phase IV observational effectiveness studies, burden of illness, transmission, pathogenesis, risk factors for illness, determinants of product effectiveness and other studies), application of novel methods and technologies, and supplementation of interventional trials where appropriate with RWE through hybrid trial designs and tokenization. This will represent significant learning experience and growth for the successful candidate. The Platform will insource this work to the fullest possible extent, so prospective candidates who have outsourced work to contract research organizations need not apply.

Within the RWE Platform, a dedicated team of RWE Scientists will support the TA teams within the Oncology category, reporting to the Solid Tumor Oncology RWE Science & Epidemiology Team Lead. Leveraging their understanding of how RWE can support the entire lifecycle from molecule to marketplace, the Solid Tumor Oncology RWE Science & Epidemiology Sr Manager will deliver timely real world insights (RWI) by understanding cross-functional pipeline / asset team’s strategic objectives and timelines, collaborate with the team and RWE Biostatistics & other relevant colleagues to generate RWE, and direct creation of easy-to-understand summary reports as directed by their supervisor. They will receive mentorship to help build or advance a nuanced understanding of real world data, what fit-for-purpose data needs are for different applications, and which sources are most appropriate for completing objectives, partnering closely with the Platforms & Partnerships and Patient Advocacy & External Partnerships teams. The RWE Scientist will ensure the development of consistent business rules and standards, versioning rules as care pathways evolve.

ROLE RESPONSIBILITIES

• As instructed, leads RWI for feasibility assessments, go/no-go decisions, co-design and create dashboards to inform cross-functional teams’ hypothesis generation, generate timely and detailed insights.

• Collaborates with team members to build strong internal and external partnerships and act as a junior subject matter expert by providing expert consultations on all aspects of RWD studies and analyses, including feasibility assessment, objectives, study design, data source identification, protocol development, statistical analyses, and table shells.

• Conduct and oversee the execution of rapid RWD-based queries and studies and effectively communicate the findings and study results to internal stakeholders using tables, visualizations, short reports, and slide decks.

• Apply quality standards and processes to manage quality, consistency, usability, security, and availability of data throughout the data lifecycle; stay up to date on RWD/E best practices.

• Participates actively on internal cross-functional teams, RWE Biostatistics, and other colleagues to create high-quality RWE from rigorously designed protocols.

• Help to collaboratively write high-quality methods, innovative approaches, protocols, and designs.

• Generate RWE through collaborations with the pipeline/asset teams (e.g., pipeline teams, Global Product Development franchise/asset teams, BU Medical affairs, HEOR, Commercial and other functions), RWE Biostatistics, and other functions as directed.

• Document all requests and track progress toward project completion, create and measure quarterly ROI metrics, and ensure support to business goals.

• 2+ (with a master’s degree) to 3+ (Bachelor’s degree) years’ experience in the pharmaceutical industry or related field in Epidemiology, Pharmacoepidemiology, or Biostatistics roles with a substantial quantitative and computational component, other related fields or commensurate professional experience.

• Proven successful track record of scientific analysis of real- world data for scientific, business, quality or other purposes

• Knowledge of Electronic Health Records, medical and pharmacy claims, patient registries, patient participating research networks and other real-world data sources

• Ability to critically evaluate analytic results against the literature, subject matter expert feedback or other reliable sources to ensure biological and medical credibility in alignment with cross-functional team strategy / priorities

• Two or more years of experience in communicating in verbal and written form with all levels of personnel with diverse backgrounds, and able to create and deliver clear presentations to teams

• Ability to work under pressure with a high level of autonomy and internal motivation and adapting rapidly within evolving digital environment

• Experience with protocol development and execution for non-interventional studies using a variety of analytical techniques applied to various databases

• Two or more years of hands-on experience of query and analytic languages and technologies (eg, SQL, R, SAS, IHD, Aetion) and of relevant biological and medical data standards (eg, HGNC / Entrez, ICD, CPT)

• Ability to rapidly learn new domains to understand the latest scientific or medical findings and incorporate them into projects as appropriate; to interpret data dictionaries and other technical documentation

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

Up to ~5% travel

ADDITIONAL DETAILS:

• Last date to apply for Job: February 16, 2024.

The annual base salary for this position ranges from $99,900.00 to $166,500.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 15.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Market Access

#LI-PFE