Why Patients Need You

Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best-in-class medicines to patients around the world.

What You Will Achieve

• As a Scale-Up Engineer/Scientist, you will provide technical support to Product and Process Technologies (PPT) with focus on scale-up issues: safety, heat transfer, agitation, reaction kinetics, distillations, extractions, filtrations, and financial analysis. You will work with teams to develop and implement manufacturing processes for active pharmaceutical ingredients.

• Another aspect of your work will be to develop/support fermentation isolation processes. Additional tasks could involve development and support of milling/micronizing and super critical CO2 processes.

• Part of your time will also be spent supporting existing active pharmaceutical manufacturing processes. This will involve supporting Quality and Operations with investigation of deviations.

• You will need to work comfortably and interchangeably on the manufacturing floor, in the laboratory, and/or office environments.

How You Will Achieve It

The Scale-Up Engineer/Scientist may be assigned to assist in the development of ad-hoc projects outside of their day-to-day responsibilities. However, core responsibilities include the following:

• Apply technical and industry-specific engineering expertise to assist scale-up of new processes.

• Improve and implement robust commercial processes to make API and intermediates; provide technical support to evaluate new processes or technology in the pilot plant as required.

• Support several existing manufacturing processes as a primary contact person.

• Execute isolation experiments to refine existing processes or define new processes. These experiments may be at laboratory (small) scale, or intermediate-scale (in Scale-up Lab).

• Learn how to perform safety evaluations.

• Gain experience with milling and micronizing, and Super-critical CO2 sterilizations.

• Act, with guidance, as technical lead for product/process technology transfers.

• Recommend and implement new/old technologies to solve process related problems.

• Adapt and respond positively to situations and people to meet changing work unit priorities.

• Author e-notebooks, reports, technical memo(s), process performance qualifications protocols presentations, reports, and technical papers with minimal direction.

• Work under general supervision, recommend actions, participate in developing experimental programs.

• Maintain laboratory and equipment in a clean, safe, functional order.

All activity will be performed consistently with Pfizer’s mission, values, and applicable policiesand guidance.

Qualifications

Must - Have

• Applicant must have a high school diploma (or equivalent) and 6 years of relevant engineering and chemistry experience OR an Associate's degree with 4 years of relevant engineering and chemistry experience OR a Bachelor's with at least 2 years of relevant engineering and chemistry experience OR master’s degree with more than 1 year of relevant engineering and chemistry experience.

• Strong aptitude for learning process technology and equipment.

• Excellent written and oral communication skills.

• Demonstrated ability to interact effectively with all levels of the organization including diverse educational and cultural backgrounds.

• Flexibility and ability to embrace and lead change.

• Ability to work in a high-paced team environment.

Nice-to-Have

• Good understanding of organic chemistry.

• Experience in a cGMP environment including specific knowledge of and experience with API manufacturing processing and equipment.

• QTS experience

• Understanding of the Kalamazoo manufacturing world.

• Familiarity with new engineering technologies and the application of these techniques and methods.

• Awareness of where to look to find relevant information.

PHYSICAL/MENTAL REQUIREMENTS

• Sitting, standing, walking, bending, ability to perform mathematical calculations and ability to perform complex data analysis. This position involves working in a laboratory environment, with limited time in the manufacturing areas, which may include standing for long periods of time and working with a variety of chemical/biological materials.
• Possible exposure to reagents, solvents, and pharmaceutical ingredients.
• Use of proper personal protection equipment (PPE) is required.

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

• Minimal travel required (less than 10%)
• Must be occasionally available to support 24/7 – operations.

Work Location Assignment:On Premise

Last Day to apply: February 7th, 2024

The annual base salary for this position ranges from $64,600.00 to $107,600.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Research and Development