Job Description

Here at Pfizer we have a specific purpose – to find breakthroughs that change patients' lives. At Pfizer we are a patient centric company, guided by our four values: courage, joy, equity and excellence.  Our breakthrough culture lends itself to our dedication to transforming millions of lives. 

One bold way we are achieving our purpose is through our company wide digital transformation strategy. We are leading the way in adopting new data, modelling and automated solutions to further digitize and accelerate drug discovery and development with the aim of enhancing health outcomes and the patient experience.

An essential component of Pfizer at Sandwich, our Pharmaceutical Sciences function supports Pfizer’s early to late stage portfolio, translating new chemical entities into commercial drug products. Pharmaceutical Sciences at Sandwich is a fully integrated Chemistry, Manufacturing and Controls capability that encompasses state of the art active pharmaceutical ingredient synthesis and drug product design as well as a cGMP manufacturing and clinical trials supply chain. Within Pharmaceutical Sciences, the Drug Product Design (DPD) department utilises expertise in analytical chemistry, materials science, formulation design, process understanding and predictive science to deliver new medicines in a variety of dosage forms. 

We are seeking a formulation and process development Senior Scientist to work in a team environment, under limited supervision of a team leader, engaged in the design, development, analysis and characterisation of predominantly parenteral pharmaceutical dosage forms.

Job Focus

You will predominantly be involved in a laboratory and pilot plant ‘hands-on’ role, working in DPD on assigned drug product and technology projects. With appropriate guidance, you will be responsible for experimental design, planning and execution of high quality work, interpretation and reporting of data and communication to enable the design, development, optimisation, scale-up and technology transfer of pharmaceutical dosage forms.  

Responsibilities

• Design and undertake high quality scientific experimentation to further the formulation and process development of parenteral dosage forms for novel drug candidates or product enhancement projects, which may include formulation, characterisation and biopharmaceutics assessment to derive appropriate data.
• Define processes for manufacture of clinical supplies and commercial drug product based on development and application of advanced process understanding and provide scientific and technical support to colleagues in GMP manufacturing facilities where appropriate.
• Contribute to the drafting of the relevant sections of the Quality modules of regulatory documentation.
• Interpret scientific data to derive clear conclusions and provide direction for future work. Provide technical support to the Pharmaceutical Sciences multidisciplinary team to facilitate and influence the development of quality drug products.
• Develop and maintain a contemporary in-depth understanding of the science, technology and regulation of parenteral pharmaceutical dosage forms and apply this knowledge to development of assigned drug candidates.
• Communicate effectively to DPD line managers and the wider development team and present data at departmental technical and governance meetings.
• Share lessons and experience with colleagues and look for opportunities to develop novel technologies, processes and digital/computational tools to advance science of formulation and process development for a variety of dosage forms.
• Ensure safe working practices are maintained both in own and others work.

Qualifications

• Degree in pharmaceutical or allied scientific discipline, with post-graduate qualification (MSc or PhD) in a relevant area (e.g. formulation, processing, dosage form characterisation) or;
• Degree in pharmaceutical or allied scientific discipline and significant practical work experience gained in an operational R&D role in pharmaceutical, drug delivery or allied industries in a relevant area (e.g. formulation, processing, dosage form characterisation).
• Recognised specialism in parenteral drug product development, e.g. formulation and process development, computational tools and digital modelling of formulation and/or process parameters, physical-chemical stability.

 
Work Location Assignment: Sandwich On Premise

Purpose 

Breakthroughs that change patients' lives... At Pfizer we are a patient centric company, guided by our four values: courage, joy, equity and excellence. Our breakthrough culture lends itself to our dedication to transforming millions of lives.  

Digital Transformation Strategy

One bold way we are achieving our purpose is through our company wide digital transformation strategy. We are leading the way in adopting new data, modelling and automated solutions to further digitize and accelerate drug discovery and development with the aim of enhancing health outcomes and the patient experience.

Flexibility  

We aim to create a trusting, flexible workplace culture which encourages employees to achieve work life harmony, attracts talent and enables everyone to be their best working self. Let’s start the conversation!  

Equal Employment Opportunity 

We believe that a diverse and inclusive workforce is crucial to building a successful business. As an employer, Pfizer is committed to celebrating this, in all its forms – allowing for us to be as diverse as the patients and communities we serve. Together, we continue to build a culture that encourages, supports and empowers our employees.

DisAbility Confident

We are proud to be a Disability Confident Employer and we encourage you to put your best self forward with the knowledge and trust that we will make any reasonable adjustments necessary to support your application and future career. Our mission is unleashing the power of our people, especially those with unique superpowers. Your journey with Pfizer starts here!