Scientist, Molecular Discovery
Pfizer Inc.
La Jolla, CA
Job posting number: #7127587
Posted: March 8, 2023
Application Deadline: Open Until Filled
Job Description
Description
Why Patients Need You
Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.
What You Will Achieve
Pfizer BioMedicine Design group at San Diego, CA is seeking an outstanding and highly motivated Scientist specialized in molecular biology and protein production to join a dynamic team in antibody discovery, optimization, and production. This role requires strong understanding and extensive hands-on skills in molecular biology and protein engineering. With your deep knowledge in the discipline, you will be an active team member who influences at the project team level. You will be using your scientific judgment to adapt standard methods and techniques by applying prior work experience and consulting others. Your ability to plan will help in preparing short-term work activities on projects. Your creativity in developing novel processes and new ideas will be used frequently. You may undertake mentoring activities to guide junior team members.
How You Will Achieve It
Work within a team on various antibody identification, optimization, and/or production projects in parallel
Implement molecular biology methods such as reformatting scFv to IgG and other modalities
Comfortable working with automation methods using liquid handling equipment
Independently design experiments, analyze data, and troubleshoot when issues arise
Present experimental design and results at internal meetings
Qualifications
Must-Have
B.S or M.S in Biological Science (Molecular Biology, Structural Biology, Protein Biochemistry, Cell Biology) or a related field (Chemistry, Chemical Engineering, Biomedical Engineering and Biological Engineering)
B.S with 6+ years or M.S with 4+ years of relevant experience in either an academic or industrial setting
Proficient in modern molecular biology techniques (primer design, vector design, PCR, gel extraction, restriction cloning, Gibson Assembly, In-Fusion, plasmid prep), particularly in antibody engineering field
Tissue-culture sterile techniques, transient expression, basic antibody purification
Track record of demonstrating analytical skills, bench skills and problem-solving skills
Understand the underlying principles of the performed experiments and document timely.
Outstanding proactive attitude, collaborative, self-aware, and strong interpersonal skills
Ability and desire to work in a fast-paced interdisciplinary scientific team and the desire to learn new techniques.
Good communication skills and ability to present research in a team setting.
Strong time management skills and ability to manage multiple projects at the same time.
Nice-to-Have
Previous experience with protein and/or antibody engineering
Previous experience with high throughput cloning, familiar with Geneious or other sequence data analysis software
PHYSICAL/MENTAL REQUIREMENTS
Lifting, sitting, standing, walking, bending, ability to perform mathematical calculations and perform complex data analysis.
Other Job Details
Work Location Assignment: On Premise colleagues work in a Pfizer site because it’s needed to get their job done. They may have flexibility to work remotely from time to time, but they are primarily on-site.
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.