Intern – Synthetic Biology and Genome Engineering

The Wyss Institute for Biologically Inspired Engineering at Harvard University

Boston, MA

Job posting number: #7122421

Posted: January 30, 2023

Application Deadline: Open Until Filled

Job Description

About the Wyss:

The mission of the Wyss Institute for Biologically Inspired Engineering at Harvard University is to transform human healthcare and the environment by emulating the way nature builds. Developed as an alliance between Harvard and other premier academic and clinical partner institutions, Institute faculty and staff collaborate in high-risk, fundamental research and science-driven technology development. A major focus of the Institute is to translate the technologies developed by its faculty and staff into commercial products and therapies through collaborations with clinical investigators and establishment of corporate alliances. For more information, visit:

Role Description:

The Wyss Institute for Biologically Inspired Engineering at Harvard University invites applications for a synthetic biology and genome engineering intern position at Dr George Church lab. The candidate will work in a multidisciplinary team, supporting the discovery of novel genome editing tools for safe and efficient gene integration into precise genomic locations in therapeutically relevant cells. The project employs library-based screens of protein-DNA interactions as well as characterization of targeted genomic insertions. The candidate will design and execute experiments, analyze experimental data, and communicate their findings to their peers and advisors in formal and informal settings.

The candidate will be mentored by post-doctoral fellows at the Wyss Institute and can expect rigorous training, exposure to multiple disciplines and in-depth learning about therapeutics, preparing them for pursuing careers in academia and industry.

In this role you will:

Perform molecular cloning experiments to generate new DNA constructs.
Culture and manipulate mammalian cells using standard tissue culture protocols.
Evaluate genome editing events using targeted and whole genome sequencing methods.
Order supplies/consumables and maintain shared stocks.
Accurately and thoroughly document experimental observations and protocols and write/update standard operating procedures.
What you’ll Need:

Knowledge/Skill: Undergraduate level biology.
Some experience with molecular biology tools is necessary.
Some experience with tissue culture is desired.
Applicants should be willing and able to work without daily supervision.
This position requires someone detail oriented and interested in problem solving.
Basic communication (written & verbal), organization (shared electronic lab notebook), and computer skills (Microsoft Office) are a must.
Where You Can Apply:

Applications, assembled as single PDF files, should contain a complete resume, cover letter describing research interests and goals, full list of publications, copies of up to three relevant scientific papers, as well as the names and contact information of three references (expected to provide letters of recommendation). Applications should be sent to [email protected] using the subject line “Intern – Genome engineering application.”

Working Conditions

Harvard requires COVID vaccination for all Harvard community members. Individuals may claim exemption from the vaccine requirement for medical or religious reasons. More information regarding the University’s COVID vaccination requirement, exemptions, and verification of vaccination status may be found at the University’s “COVID-19 Vaccine Information” webpage:

Harvard University is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, gender identity, sexual orientation, pregnancy and pregnancy-related conditions, or any other characteristic protected by law. Demonstrates a commitment to diversity, inclusion, and cultural awareness through actions, interactions, and communications with others.

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