Rivera Laboratory Postdoctoral Research Fellowship in Cancer Epigenomics

Massachusetts General Hospital Cancer Center & Harvard Medical School

Boston, MA

Job posting number: #7107032

Posted: August 2, 2022

Job Description

The Rivera laboratory at Massachusetts General Hospital Department of Pathology and Harvard Medical School is seeking highly motivated scientists for a position as Postdoctoral Research Fellow. Our laboratory, which is also affiliated with the MGH Cancer Center and the Broad institute, is focused on studying gene regulation mechanisms in cancer using epigenomic approaches. Our studies combine biochemistry and cell biology with genome-wide assays of chromatin states (such as ChIP-seq, HiChIP, HiC, ATAC-seq and RNA-seq) and epigenome editing technologies.

Work in our laboratory has uncovered critical oncogenic mechanisms in a variety of tumor types, including: pioneer functions of oncogenic transcription factors (Riggi et al, Cancer Cell 2014; Boulay et al, Cancer Discovery 2017), the role of disordered prion-like domains in gene activation (Boulay et al, Cell 2017), induction of tumor-specific active enhancers at repetitive elements (Riggi et al, Cancer Cell 2014; Tak et al, Cell Genomics 2022) and interactions between oncogenes and developmental transcription factors (Moller et al, Nature Communications 2022).

Postdoctoral Fellows will join a collaborative group of scientists working on cutting edge research. Ideally, candidates should have a strong background in molecular and cellular biology. Experience in gene regulation and next-generation sequencing technologies is preferred but not required.

To apply, please send a cover letter, a CV with a list of publications and reference letters or e-mail contacts for references to [email protected] and [email protected]

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