Research Technician II

Baylor College of Medicine

Houston, TX

Job posting number: #7104907 (Ref:12303-en_US)

Posted: July 9, 2022

Application Deadline: Open Until Filled

Job Description


The goal of this project is to model a human disease in fruit flies. The Research Technician II will work with two senior postdoctoral fellows and perform sophisticated cloning experiments to insert human cDNAs in vectors, create variants, deletions, and produce the corresponding transgenic flies using genetic crosses. Will then determine where the genes are expressed by immunostaining and perform the confocal microscopy to assess where the gene is expressed and where the proteins are localized subcellularly. Using genetic crosses other mutants will be intercrossed with these transgenic stocks to suppress or enhance the observed phenotypes. Finally, the data that are observed in flies will be extrapolated in human cultured cells to assess if the models generated in flies are evolutionarily conserved.

Job Duties

  • Performs molecular biology experiments, transgenesis experiments with flies, extensive genetic crosses with flies, immunostaining of fly tissues, confocal microscopy, maintains fly stocks.
  • Prepares and conducts laboratory research experiments.
  • Collects, compiles and analyzes data
  • Documents results of experiments.

Minimum Qualifications

  • Bachelor's degree in a Basic Science or related field. Four years of related experience may substitute for degree requirement.
  • No experience required.

Preferred Qualifications

  • Bachelor or Master in biology (Molecular Biology, Genetics, Neuroscience, Cell Biology)



Baylor College of Medicine requires employees to be fully vaccinated -subject to approved exemptions-against vaccine-preventable diseases including, but not limited to, COVID-19 and influenza.


Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.



Baylor College of Medicine fosters diversity among its students, trainees, faculty and staff as a prerequisite to accomplishing our institutional mission, and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. - Diversity, respect, and inclusiveness create an environment that is conducive to academic excellence, and strengthens our institution by increasing talent, encouraging creativity, and ensuring a broader perspective. - Diversity helps position Baylor to reduce disparities in health and healthcare access and to better address the needs of the community we serve. - Baylor is committed to recruiting and retaining outstanding students, trainees, faculty and staff from diverse backgrounds by providing a welcoming, supportive learning environment for all members of the Baylor community.

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