Research Fellow

University of Leeds

Leeds, United Kingdom

Job posting number: #7100449 (Ref:MHLMR1078)

Posted: May 20, 2022

Job Description

Do you have a strong background in cell and molecular biology? Would you like to investigate and manipulate cellular signalling, with a view to improving cancer outcomes?

The Hughes group (https://www.researchgate.net/profile/Thomas-Hughes https://medicinehealth.leeds.ac.uk/medicine/staff/452/dr-thomas-a-hughes) has a strong track-record of translational cancer research, especially in the field of breast cancer. We now have an opportunity, funded by Breast Cancer Now, for an enthusiastic researcher to join the group to advance a novel approach for improving chemotherapy responses in breast cancer.  We have identified one of the ways by which some breast cancer cells become resistant to chemotherapy - by receiving signals from stromal cancer associated fibroblasts that drive chemoresistance [see Broad et al (2021) Brit J Cancer 124, 1110–20]. We now aim to develop and validate therapeutic approaches to inhibit this stromal-induced resistance. 

To explore the post further or for any queries you may have, please contact: 

Thomas Hughes, Associate Prof of Cancer Biology, and project leader

Tel: +44 (0)113 3431984, Email: [email protected]     

The University of Leeds is committed to providing equal opportunities for all and offers a range of family friendly policies. The School of Medicine holds a Gold Athena Swan award.   We are committed to being an inclusive Medical School that values all staff, and we are happy to consider job share applications and requests for flexible working arrangements from our employees.

As an international research-intensive university, we welcome students and staff from all walks of life and from across the world. We foster an inclusive environment where all can flourish and prosper, and we are proud of our strong commitment to student education. Within the Faculty of Medicine & Health we are dedicated to diversifying our community and we welcome the unique contributions that individuals can bring, and particularly encourage applications from, but not limited to Black, Asian, people who belong to a minority ethnic community, people who identify as LGBT+; and people with disabilities. Candidates will always be selected based on merit and ability.

Location:  Leeds - St James University Hospital
Faculty/Service:  Faculty of Medicine & Health
School/Institute:  Leeds Institute of Medical Research (LIMR)
Section:  Molecular Medicine
Category:  Research
Grade:  Grade 7
Salary:  £34,304 to £40,927 p.a.
Working Time:  100%fte
Post Type:  Full Time
Contract Type:  Fixed Term (available until 31 May 2025)
Release Date:  Thursday 19 May 2022
Closing Date:  Thursday 09 June 2022
Reference:  MHLMR1078


The University community is made up of a wide range of people with diverse backgrounds and circumstances, which we value and regard as a great asset. As part of our continued commitment to equality and inclusion, we strive to create an environment where everyone can reach their full potential and have a real opportunity to participate in and contribute to our activities.


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