Postdoctoral Fellow -T cell Function within Drug Development and Immunology

City of Hope

Duarte, CA

Job posting number: #7087450 (Ref:10011117-2)

Posted: October 20, 2021

Application Deadline: Open Until Filled

Job Description

About City of Hope

City of Hope, an innovative biomedical research, treatment and educational institution with over 6000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary

The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. Our lab is focused on studying ROR g t-dependent Th17 immunity, referring to (Nature Immunology, https://www.ncbi.nlm.nih.gov/pubmed/28846085 ; Nature Communications: https://www.ncbi.nlm.nih.gov/pubmed/30451821 ; PNAS, https://www.ncbi.nlm.nih.gov/pubmed/29282318 ; Journal of Immunology, https://www.ncbi.nlm.nih.gov/pubmed/30567733) .

Our research topics are closely related to the development of drugs for treatment of autoimmunity. The recent postdoctoral fellows from this lab were recruited by pharmaceutical companies such as Eli Lilly and academic institutions as faculty. Experimental approaches require the candidate to be familiar with basic immunology knowledge as well as techniques for the manipulation of T cells.

This laboratory is located at the Beckman Research Institute of City of Hope, a NIH-designated comprehensive cancer center with state-of-the-art facilities and friendly environments. Our institute is located within the greater Los Angeles area, where you will enjoy the diversity of culture and lifestyle in warm southern California.

This role will require 10% travel.

Key Responsibilities:
  • Perform analysis of T cell activation and differentiation
  • Perform RNA-seq and ChIP-seq analysis of transcription factor-regulated gene expression.
  • Handle mouse model of autoimmunity
  • Perform regular tissue culture and molecular biology experiments.
  • Perform computer-based analysis of high throughput sequence data.


Basic education, experience and skills required for consideration:
  • A Ph.D. degree in life or biomedical sciences, or a related discipline is required.
  • Candidate shall have publication records to demonstrate the academic excellence in research.


Additional Information:
  • For more information on Dr. Zuoming Sun's research please visit here
  • To protect the health of patients and staff and to comply with new State of California mandates, City of Hope staff are required to show proof of full vaccination by September 30, 2021. Compliance is a condition of employment.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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  • Posting Date: Jun 22, 2021
  • Job Field: Research
  • Employee Status: Regular
  • Shift: Day Job


City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.


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