Research Assistant III - Host/Epithelial-Microbiome Interactions

Harvard Medical School

Boston, MA

Job posting number: #7081562

Posted: July 23, 2021

Application Deadline: Open Until Filled

Job Description

About Us:

The Wyss Institute’s mission is to transform healthcare and the environment by emulating the way nature builds. We harness the freedom of academia and the focus of industry in order to translate revolutionary technologies into commercial products and solutions. At the Wyss Institute, faculty from premier academic and clinical institutions, collaborate with staff scientists, postdocs, graduate students, industry experts, business development leaders, and entrepreneurs across disciplines to invent and de-risk new technologies that don’t just succeed at making it to the market – they disrupt it. We support research that universities, companies, and venture capital firms don’t fund because they view it as too risky. We prefer to use the word “challenging,” and we love challenges. For more information, visit: http://wyss.harvard.edu/



About You:

You are a collaborative, impact-focused problem solver who wants to be part of a dynamic team dedicated to creating and commercializing novel approaches to global challenges in health care and sustainability. You want the freedom to explore, to push the boundaries of what is possible, and to use your ambition to tackle challenging projects in a fast-paced, industry-focused environment without a lot of administrative hurdles. You enjoy working with diverse groups of people and leveraging your expertise to create innovations that can change the world.



About the role:

We are currently seeking a Research Assistant to significantly contribute to a research program funded by the Bill and Melinda Gates Foundation involving the use of microfluidic cell based in vitro models to study the role the microbiome and immune component on the intestinal and vaginal epithelium. As part of the Bioinspired Therapeutics & Diagnostics platform and reporting to the Staff Scientist, you will manage primary cell cultures, including, but not limited to, primary intestinal organoids or vaginal and cervical epithelial cells and organ specific endothelial cells. You will be expected to learn new skills, and troubleshoot any technical issues that arise, and contribute intellectually to the project. For more information, visit: https://wyss.harvard.edu/focus-area/biomimetic-therapeutic-diagnostics/


Job-Specific Responsibilities

What you’ll do:

With supervision, plan and execute scientific research dealing with microfluidic organ on chip primary cell culture and microbiome co- culture.
Working independently under the supervision of staff and team members, execute endpoint assays, including, but not limited to, cell based qPCR/TaqMan, ELISA, westerns, enzymatic assays, imaging, and flow cytometry.
Order supplies and perform support activities and lab maintenance.
Under the supervision of staff, contribute to data analysis and present data and conclusions at meetings within the Wyss Institute
Demonstrate a commitment to diversity, inclusion, and cultural awareness through actions, interactions, and communications with others.

Basic Qualifications

What you’ll need:

Bachelor’s degree in cell biology or bioengineering
At least two years of experience involving aseptic primary human cell culture and molecular biology techniques, such as ELISA, PCR, microscopy or related experience required. Advanced Education may count towards years of experience.

Additional Qualifications and Skills

Desirable Skills:

Master's degree in Cell Biology or Bioengineering strongly preferred.
Previous experience with primary mammalian cell culture is required. Candidates with experience in multiple primary cell types and lung diseases strongly preferred.
Experience with cell culture using a microfluidic device is preferred.
Proficiency with personal computers and applicable software packages (Microsoft Office).
Good written and oral communication skills are essential.
Ability to function in a team-oriented environment with other scientists and staff at the Institute is a must.
Highly motivated, detail-oriented, organized, and able to take initiative.



Harvard Medical School strives to cultivate an environment that promotes inclusiveness and collaboration among students, faculty and staff and to create new avenues for discussion that will advance our shared mission to improve the health of people throughout the world.


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