CSIRO Postdoctoral Fellowship in Synthetic Polymer and Bioconjugation Chemistry

Commonwealth Scientific & Industrial Research Organisation (CSIRO)

Melbo, Australia

Job posting number: #7081490 (Ref:cj_75475)

Posted: July 22, 2021

Application Deadline: Open Until Filled

Job Description

The Opportunity


  • Do you have a PhD in chemistry or a related field?
  • Like the idea of being involved in developing next generation biologic drug candidates?
  • Join our Biomedical Manufacturing Program at CSIRO for this exciting postdoctoral role


CSIRO Early Research Career (CERC) Postdoctoral Fellowships provide opportunities to scientists and engineers who have completed their doctorate and have less than three years of relevant postdoctoral work experience. These fellowships aim to develop the next generation of future leaders of the innovation system.


Biologic drugs are an increasingly important class of therapeutics used in a range of applications from vaccines to chemotherapy. The Postdoctoral Fellow will be involved in developing next generation biologic drug candidates through incorporation of polymeric materials and other important functionalities.


The Postdoctoral Fellow will join the Biomedical Manufacturing Program within the CSIRO Manufacturing Business Unit, supported by a highly multidisciplinary team. While the Postdoctoral Fellow’s focus will be in synthetic bioconjugation chemistry, they will be supported in this work by a wide variety of expertise in areas such as polymer chemistry, materials science, microbiology, pharmacology, and cell biology. The project has a strong translational focus, with the aim of Intellectual Property generation and ultimately commercialisation of technologies developed within.


Your duties will include:

  • Using rational design and bioconjugation knowledge, proposing novel synthetic targets as candidate materials in consultation with the team.
  • Planning and performing synthetic chemistry experiments to generate novel therapeutics.
  • Performing biochemical and/or enzymatic assays, and employing spectroscopic and chromatographic techniques, to characterise the structure and behaviour of the novel materials.
  • With guidance from team members, performing microbiological testing of candidate materials in bacterial culture.
  • Using structure-activity relationships to screen, optimise, and identify leads from prepared candidates.


Location: Clayton, Melbourne

Salary: AU$88k - AU$96k plus up to 15.4% superannuation

Tenure: Specified term of 3 years

Reference: 75475

To be considered you will need:

  • A doctorate (or will shortly satisfy the requirements of a PhD) in a relevant discipline area, such as chemistry or a related field. Please note: To be eligible for this role you must have no more than 3 years (or part-time equivalent) of postdoctoral research experience.
  • Demonstrated experience and problem-solving skills in bioconjugation of macromolecules and/or biopolymers and purification methods thereof.
  • Strong organic and/or polymer synthesis skills.
  • Knowledge of, and/or experience with, bioanalytical techniques (including one or more from SDS-PAGE, ELISA, Western blot, colorimetric assays, circular dichroism, tryptophan fluorescence, FRET analysis, or isoelectric point determination).
  • Experience with polymer and small molecule characterisation (e.g. NMR, SEC, FT-IR, MS, MALDI-ToF, etc.).


For full details about this role please view the Position Description


To be eligible to for role, you must be an Australian/New Zealand Citizen, Australian Permanent Resident or Australian temporary resident currently residing in Australia and be able to commence in the role by December 2021/January 2022.

The successful applicant will be required to obtain and provide a National Police Check or equivalent.


Flexible Working Arrangements

We work flexibly at CSIRO, offering a range of options for how, when and where you work. 

Diversity and Inclusion

We are working hard to recruit people representing the diversity across our society, and ensure that all our people feel supported to do their best work and feel empowered to let their ideas flourish. 


At CSIRO Australia's national science agency, we solve the greatest challenges through innovative science and technology. We put the safety and wellbeing of our people above all else and earn trust everywhere because we only deal in facts. We collaborate widely and generously and deliver solutions with real impact. 

Join us and start creating tomorrow today!

How to Apply

Please apply on-line and provide a cover letter and CV that best demonstrate your motivation and ability to meet the requirements of this role.

Applications Close

31 August 2021, 11:00pm AEST

We’re working hard to build a safe and welcoming culture where people can bring their whole selves to work. Valuing and enabling difference empowers our people, unlocking their potential to innovate and shape the future for our customers, all Australians and the world. We do the extraordinary every day. We innovate for tomorrow and help improve today. We're the people that stay awake solving the world’s big questions. This is true of our science and of our people. Our mission is to create benefit for Australia through impactful science and innovation but we know that that's not possible without an inclusive and diverse culture. We're working hard to recruit diverse people and ensure all our people feel supported to do their best work and empowered to let their ideas flourish.

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More Info

Job posting number:#7081490 (Ref:cj_75475)
Application Deadline:Open Until Filled
Employer Location:CSIRO
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