Research Assistant I - Biochemistry - Westbrook Lab (90004976)

Baylor College of Medicine

Houston, TX

Job posting number: #7081456 (Ref:7863-en_US)

Posted: July 21, 2021

Application Deadline: Open Until Filled

Job Description


The Westbrook Lab is seeking talented cell and molecular biologists to work in an interdisciplinary team environment on the discovery and development of new therapeutic strategies for cancer. In particular, this work will focus on understanding how cancer driver perturbations a) cause changes in the transcriptomic, proteomic, and epigenomic profiles of cells from various tissues and b) how these changes lead to tissue-specific, tumor-selective vulnerabilities that can be exploited as new therapeutic entrypoints.

Job Purpose

Performs responsible research work that requires planning, completing, and occasionally supervising limited research projects in accordance with general plans approved by the supervisor.

Job Duties

  • Plan, execute and analyze experimental protocols to characterize the phenotypic and molecular consequences of gene of interest perturbation.
  • Generate constructs required for assigned experiments via molecular cloning techniques including standard restriction, Gateway and Gibson technologies.
  • Document and communicate experimental results and progress.
  • Conduct literature searches and summarize information in an appropriate format for a particular study.
  • Annotate and maintain collaborative protocol repositories for all lab members.
  • Work collaboratively with chemical and molecular biologists to engineer and characterize cancer cell lines.
  • Oversee the maintenance of lab equipment and environment.
  • Assign activities to less experienced research staff.
  • Clean and maintain laboratory equipment, supplies and work areas.

Minimum Qualifications

  • Bachelor's degree in a Basic Science or a related field.
  • Two years of relevant experience.

Preferred Qualifications

  • Master's degree in a related field.
  • Expertise in mammalian cell culture with a variety of cell types and growth conditions including meticulous sterile technique and attention to detail.
  • Expertise in lentiviral/retroviral production, genetic perturbation techniques including RNAi and CRISPR/CAS9 technologies, stable cell line generation/maintenance, transfection/electroporation, DNA/RNA/protein extraction, western blot, qPCR, and standard subcloning.
  • Competency in one or more key areas including:  molecular biology, cell line engineering, and cancer biology.


  • Work independently and effectively in a highly dynamic, multi-disciplinary environment.





Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.



Baylor College of Medicine fosters diversity among its students, trainees, faculty and staff as a prerequisite to accomplishing our institutional mission, and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. - Diversity, respect, and inclusiveness create an environment that is conducive to academic excellence, and strengthens our institution by increasing talent, encouraging creativity, and ensuring a broader perspective. - Diversity helps position Baylor to reduce disparities in health and healthcare access and to better address the needs of the community we serve. - Baylor is committed to recruiting and retaining outstanding students, trainees, faculty and staff from diverse backgrounds by providing a welcoming, supportive learning environment for all members of the Baylor community.

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More Info

Job posting number:#7081456 (Ref:7863-en_US)
Application Deadline:Open Until Filled
Employer Location:Baylor College of Medicine
United States
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