Research Assistant II - Biochemistry - Westbrook Lab (90004976)

Baylor College of Medicine

Houston, TX

Job posting number: #7080346 (Ref:7404-en_US)

Posted: June 23, 2021

Application Deadline: Open Until Filled

Job Description


The Therapeutic Innovation Center is seeking talented cell and molecular biologists to work in an interdisciplinary team environment on early therapeutic and drug discovery projects. As our key focus is on diseases of gene regulation, with an emphasis on cancer, this position will involve the study of phenotypes associated with target perturbation in engineered cancer cell line and mouse models. Candidates will be expected to plan, execute and analyze assigned experiments with minimal supervision and to be able to troubleshoot as needed.

Job Purpose

Performs responsible research work of a complex nature that requires establishing test methods and procedures as well as planning, completing, and occasionally supervising limited research projects in accordance with general plans approved by the supervisor.

Job Duties

  • Plans and executes experimental protocols in mammalian cell culture including lentiviral production, cell growth/death assays and maintaining cell stocks.
  • Plans and executes standard molecular biology protocols including subcloning (Gateway, Topo, etc), qRT-PCR, PCR, DNA/RNA/protein isolation from cells and tissues.
  • Evaluates and analyzes data associated with assigned experiments.
  • Clearly documents and communicates (oral and written) experimental results and progress to principal investigators.
  • Assists in the preparation of laboratory reports.
  • Works collaboratively and effectively in a highly dynamic, multi-disciplinary environment.
  • Cleans and maintains laboratory equipment, supplies and work areas.
  • Handle biohazards or risks for potential job-related injury, such as those found in an ordinary laboratory environment.

Minimum Qualifications

  • Bachelor's degree in a Basic Science or a related field. 
  • Three years of relevant experience is required.

Preferred Qualifications

  • Master's degree in a related field.
  • Experience with mammalian cell culture, experience with a variety of cancer and/or normal cell types and growth conditions including meticulous sterile technique and attention to detail.
  • Experience with genetic perturbation techniques including RNAi and CRISPR/CAS9 technologies, lentiviral/retroviral production and stable cell line generation/maintenance.
  • Experience with handling mice and general animal care techniques including genotyping, tumor measurement and IP injections.
  • Experience with the following techniques: transfection/electroporation, DNA/RNA/protein extraction, western blot, qPCR, and standard subcloning (restriction digest based, Gateway, Topo etc).





Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.



Baylor College of Medicine fosters diversity among its students, trainees, faculty and staff as a prerequisite to accomplishing our institutional mission, and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. - Diversity, respect, and inclusiveness create an environment that is conducive to academic excellence, and strengthens our institution by increasing talent, encouraging creativity, and ensuring a broader perspective. - Diversity helps position Baylor to reduce disparities in health and healthcare access and to better address the needs of the community we serve. - Baylor is committed to recruiting and retaining outstanding students, trainees, faculty and staff from diverse backgrounds by providing a welcoming, supportive learning environment for all members of the Baylor community.

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