Staff Scientist - Lymphoma Translational Research
Job posting number: #7062848 (Ref:10005173)
Posted: December 17, 2019
Application Deadline: Open Until Filled
City of Hope, an innovative biomedical research, treatment and educational institution with over 6000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.
Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment.
Dr. Danilov's research is highly translational and involves work with primary samples from patients with lymphoma. Based on laboratory findings, Dr. Danilov's group originates early-phase clinical trials, allowing for verification of laboratory findings in the clinical setting. The translational project will focus on cancer cell signaling and investigate novel molecular targets in B-cell malignancies. The areas of interest in the laboratory are:
- novel targets within the ubiquitin-proteasome pathway;
- mechanism of action and resistance to transcriptional CDKs.
This position is created to continue research studies currently funded by the Leukemia and Lymphoma Society Translational Research Program Award and Scholar Award. This grant focuses on understanding how sumoylation regulates metabolism in B-cell neoplasia. The ideal candidate will have extensive experience in the field of metabolism and cancer cell signaling, and be familiar with mouse modeling techniques. He or she should have a successful track record of publications and must have demonstrated collaborative skills, as demonstrated in multiple collaborative publications.
Highly-motivated candidates with expertise in molecular biology, hematopoiesis, and in vivo models who are interested in a career in oncology basic/translational research will be most competitive for this position.
- Responsible for leading a collaborative research project focused on extrinsic mechanisms and drug resistance.
- Maintaining a high level of professional expertise in the field; supervising and providing guidance and mentorship to other researchers within the laboratory; designing and directing or executing experiments; and establishing laboratory procedures and systems that enforce and maintain a high level of organization in the lab.
- Demonstrate success in leading, managing and participating in collaborative projects and a distinguished record of scientific and technical accomplishments.
Basic education, experience and skills required for consideration:
- Must have the U.S. equivalent bachelor's or master's degree in an appropriate discipline, and will often have a Ph.D. or other doctoral level degree.
- Must have at least 3 years of post-graduate research experience in the relevant field. They are likely to have deep expertise in a singular area of focus but may also have worked as boundary spanners across multiple fields
- Demonstrated a satisfactory track record of scholarly activity including high-quality peer-reviewed publications
- Must be actively engaged in publishing high-quality manuscripts, the development and submission of grant/funding proposals and leading projects that are aligned with the lab's focus area.
- Expertise with molecular biology and in vivo models will be required for this project.
City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.