Postdoctoral Fellow Positions in Tumor Metastasis
San Diego, CA
Job posting number: #7057007
Posted: April 16, 2019
Application Deadline: Open Until Filled
Job DescriptionPOSTDOCTORAL FELLOW POSITIONS IN TUMOR METASTASIS are available immediately for highly motivated and creative young scientists to investigate the molecular basis of tumor dissemination and metastasis dormancy. Specifically, our previous work show that two cellular programs, Epithelial-Mesenchymal Transition (EMT) and invadopodia-mediated extracellular matrix degradation play critical roles in tumor metastasis. We identified a number of upstream regulators of EMT and invasion, such as matrix stiffness and epithelial polarity. We recently established novel mouse models to study breast cancer metastasis dormancy regulation by immune cells and other stroma signals. Various projects are available to utilize 3D organoids, mouse tumor models, cell and molecular biology tools, functional genomics, and advanced imaging techniques to uncover novel biochemical and biomechanical signaling pathways responsible for tumor dissemination and metastasis dormancy. For more information about our lab, please see: https://sites.google.com/site/ucsdyanglab/
Eckert et al., 2011, Cancer Cell (PMC3072410); Tsai et al., 2012, Cancer Cell (PMC3522773); Wei et al., 2015, Nature Cell Biology (PMC4452027); Jung et al., 2019, Nature Cell Biology (DOI:10.1038/s41556-019-0291-8).
Successful candidate must hold a recently obtained PhD-level degree with strong background in cell biology, biochemistry, and molecular biology. Experience with animal models of cancer, immunology, and bioinformatics is desirable. Applicants should send a CV and the names and contact information of three references to:
Jing Yang, Ph.D.
Moores Cancer Center
University of California, San Diego
La Jolla, CA, USA