Process Development Scientist - Cell Culture

Pfizer Inc.

Grange Castle, Ireland

Job posting number: #7135287 (Ref:pf-4857347)

Posted: March 21, 2023

Application Deadline: Open Until Filled

Job Description

Closing date: 25th March 2023

Why Patients Need You

Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

What You Will Achieve

As a Senior Associate Scientist, you will be at the centre of our operations and you’ll find that everything we do, every day, is in line with an unwavering commitment to quality. You will provide science and technology expertise in the disciplines of cell culture sciences for the development and optimization of protein manufacturing processes. 

You will help Pfizer develop new and improved processes used in the research and development of our drugs. Your innovative mindset will help us develop economical, efficient and safe processes. Your significant experience of applying knowledge of principles, concepts, and practices of the discipline will make you a critical member of the team. You are proactive in contributing to all team discussions and creating an environment of collaboration.

It is your innovative scientific temperament that will help in making Pfizer ready to achieve new milestones and help patients across the globe.

How You Will Achieve It

  • Comply with safety and regulatory requirements is expected and documented through the internal training program.
  • Develop and optimise robust cell culture processes via experimental investigations at 5 – 750 L production scales.
  • Operation of mammalian cell culture processes up to 750 L scale within the Pilot Lab according to pre-defined procedures.
  • Apply knowledge of cell culture technologies, bioprocess engineering and biochemistry to cell culture process development projects.
  • Collaborate closely with analytical scientists who work on the characterization of proteins during process development studies.
  • Provide technical guidance such as direction of laboratory investigational studies, process and experimental design and new technology development. 
  • Provide technical support to Drug Substance Technical Services when required during investigations, new process introduction or change implementation in commercial manufacturing operations.  Technical support may involve trouble-shooting manufacturing-scale process problems through experimental investigations at laboratory scales of operation.

Qualifications

Must-Have

  • BEng / BSc / MSc / PhD in Biotechnology / Chemical Engineering / Biochemical Engineering or other related disciplines. 
  • Technical fields of experience preferably to include specific knowledge and practical experience of some of the following: mammalian cell technology, biochemistry, cell biology, microbial fermentation, genetics, fluid mechanics, process modeling.
  • 0-3+ years of directly relevant experience in the biopharmaceutical industry
  • Ability to troubleshoot technical issues, plan and carry out experiments independently, and work with complex instrumentation and software
  • Excellent oral and written communication skills
  • Strong process and computer skills

Nice-to-Have

  • Experience in designing and executing components of experimental programs in the laboratory.
  • Familiar with problem-solving, risk analysis and statistical tools

  
Work Location Assignment: On Premise

Additional Information 

  • In order to be considered for this position in Ireland you need to be legally eligible to work in Ireland. 

  • Please note there is no relocation support available for this position 

 

How to apply 

  • Make a difference today, all suitable candidates should apply with CV below.  We are looking forward to hearing from you! 

Purpose  

Breakthroughs that change patients' lives... At Pfizer we are a patient centric company, guided by our four values: courage, joy, equity and excellence. Our breakthrough culture lends itself to our dedication to transforming millions of lives. 

Digital Transformation Strategy

One bold way we are achieving our purpose is through our company wide digital transformation strategy. We are leading the way in adopting new data, modelling and automated solutions to further digitize and accelerate drug discovery and development with the aim of enhancing health outcomes and the patient experience. 

Equal Employment Opportunity

We believe that a diverse and inclusive workforce is crucial to building a successful business. As an employer, Pfizer is committed to celebrating this, in all its forms – allowing for us to be as diverse as the patients and communities we serve. Together, we continue to build a culture that encourages, supports and empowers our employees. 

Research and Development

#LI-PFE


Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.


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