The oral microbiota is emerging as an important driver of local and systemic inflammatory disease. In the Apollo (Stacy) Lab, we decipher metabolic communication between the oral microbiota and host in the settings of gum disease (periodontitis) and oral cancer. In particular, we analyze how host-derived metabolites shape the ecological balance between commensals and pathogens, and how this balance in turns tunes host immune responses. We leverage an interdisciplinary approach involving bacterial genetics, genomics, animal models, immune profiling, and human samples. Our long-term goal is to translate host-derived metabolites into microbiota-directed therapies.
 

Principal Investigator: Apollo Stacy, PhD

Lerner Research Institute Department: Cardiovascular & Metabolic Sciences 

Lab Research Topics:

• Microbiology
• Microbiome
• Immunology
• Periodontitis
• Cancer
• For more information about the lab’s research, please visit: https://www.theapollolab.com or contact Apollo Stacy at [email protected]

Job Responsibilities:

• Project design with the goal of data generation, analysis, interpretation
• Preparing, collecting, and maintaining required research project documentation and data
• Leading, assisting, and contributing to the preparation of internal and external presentations, reports, and manuscript publications

Education:

• PhD or MD/PhD required
• MD with relevant laboratory experience may substitute for PhD

Languages:

• English Proficiency proof required for candidates arriving on J-1, J-2, or F1 + OPT visa status

Work Experience:

• Previous experience in a research or academic setting.  Graduate student experience meets this requirement.
• Scientific writing experience

Additional Preferred Qualities:

• Highly self-motivated
• Works well in team environment
• Experience with mouse models
• Microbial genetics/genomics
• Strong communication skills

Personal Protective Equipment:

• PPE per institutional requirements; may vary by laboratory

Preferred Application Materials:

All application materials should be submitted directly via email to Apollo Stacy at [email protected].

• CV
• Brief description of research interests and career goals
• Contact info for 3 references

Keywords: Postdoc, Research, LRI, Polymicrobial interactions, Bacterial metabolism, Tn-seq, Metagenomics, Metatranscriptomics, Metabolomics, Flow cytometry