Research Technician III - Pediatrics - Nutrition (90002446)

Baylor College of Medicine

Houston, TX

Job posting number: #7091367 (Ref:9850-en_US)

Posted: January 5, 2022

Application Deadline: Open Until Filled

Job Description

Summary

A Research Technician III position is available in Dr. Xia Gao’s laboratory at Baylor College of Medicine in the Department of Pediatrics. Our laboratory uses analytical chemistry, biochemistry, molecular biology, cell culture, and mouse physiology to understand dietary inputs in tumor onset, progression and treatment. The goal is to identify nutritional interventions and metabolic pathways for prevention and treatment of cancer. We employ untargeted and targeted metabolomic analysis and isotope tracing studies using newly vested in-house Thermo Exploris 480 LC/MS instrument. Along with this powerful analytical tool, we use various in vivo mouse models and in vitro models to define the role of nutritional input and the underlying mechanisms in cancer development and control. We have recently (Nature, 2019) employed metabolomics approaches to show that dietary methionine restriction is an effective and feasible dietary intervention in healthy humans and mice to alter circulating metabolism without overt side effect. Dietary methionine restriction has shown promising in various mouse cancer models alone or in combination with chemotherapy or radiotherapy.  The research technicians are expected to conduct experiments and downstream data analysis and presentation: LC-MS analysis, or animal studies, and/or other standard molecular biology procedures such as DNA, RNA, and protein isolation, qPCR, western blotting, immunofluorescence staining, and cell culture.

Job Duties

  • Prepares and conducts laboratory research experiments.
  • Collects, compiles and analyzes data
  • Conducts literature searches and summarizes information in an appropriate format for a particular study.
  • Documents results of experiments.
  • Selects, evaluates and applies techniques used in routine research.
  • Orders laboratory supplies and equipment.

Minimum Qualifications

  • Bachelor's degree in a Basic Science or related field. Four years of related experience may substitute for degree requirement.
  • One year of relevant experience.

Preferred Qualifications

  • Previous experience with analytical chemistry especially with LC-MS, mouse cancer models, and cell culture in a research lab.
  • A minimum of 2-year commitment is required and longer term of commitment is preferred.

 

 

Baylor College of Medicine requires employees to be fully vaccinated -subject to approved exemptions-against vaccine-preventable diseases including, but not limited to, COVID-19 and influenza.

 

Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.

 9850

CA 



Baylor College of Medicine fosters diversity among its students, trainees, faculty and staff as a prerequisite to accomplishing our institutional mission, and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care. - Diversity, respect, and inclusiveness create an environment that is conducive to academic excellence, and strengthens our institution by increasing talent, encouraging creativity, and ensuring a broader perspective. - Diversity helps position Baylor to reduce disparities in health and healthcare access and to better address the needs of the community we serve. - Baylor is committed to recruiting and retaining outstanding students, trainees, faculty and staff from diverse backgrounds by providing a welcoming, supportive learning environment for all members of the Baylor community.


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